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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBB1
All Species:
20.61
Human Site:
S218
Identified Species:
50.37
UniProt:
O00213
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00213
NP_001155.1
710
77244
S218
G
M
R
N
S
A
A
S
D
E
D
S
S
W
A
Chimpanzee
Pan troglodytes
XP_521814
848
91186
S351
G
M
R
N
S
A
A
S
D
E
D
S
S
W
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534037
724
78741
A233
N
R
P
G
A
A
V
A
E
E
T
L
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXJ1
710
77450
S218
G
M
R
N
S
A
A
S
D
E
D
S
S
W
A
Rat
Rattus norvegicus
P46933
711
77638
S219
G
M
R
N
S
A
A
S
D
E
D
S
S
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507097
616
68316
R155
D
L
P
P
G
W
K
R
I
S
D
I
A
G
F
Chicken
Gallus gallus
XP_420735
740
81441
N199
E
D
K
S
A
Q
S
N
S
Q
A
S
T
I
I
Frog
Xenopus laevis
NP_001087003
610
66956
S149
G
M
R
N
N
G
G
S
D
E
D
S
S
W
A
Zebra Danio
Brachydanio rerio
XP_693392
869
95380
S384
R
I
Q
N
L
P
H
S
D
E
E
S
S
W
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787988
848
93773
V209
S
V
S
D
S
S
E
V
E
G
E
S
H
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
N.A.
78.3
N.A.
94.6
93.8
N.A.
38.8
45
51.5
39.5
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
83.7
N.A.
80.6
N.A.
97.1
96
N.A.
53.6
60.9
62.2
53.5
N.A.
N.A.
N.A.
N.A.
47.1
P-Site Identity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
6.6
6.6
80
46.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
40
N.A.
100
100
N.A.
20
53.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
50
40
10
0
0
10
0
10
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
0
0
60
0
60
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
20
70
20
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
50
0
0
10
10
10
10
0
0
10
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
10
0
10
10
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
60
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
20
10
0
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
10
0
0
10
0
0
0
10
0
0
10
0
0
% Q
% Arg:
10
10
50
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
50
10
10
60
10
10
0
80
60
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% T
% Val:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
60
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _